Purified anti-Cytokeratin (pan reactive) 628602 from BioLegend

Product Specs
ItemPurified anti-Cytokeratin (pan reactive)
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number628602
NCBI Gene AliasesCK-18, CYK18, K18
FormatThis antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml
CloneC-11
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (IHC)-P
Conjugate/TagUnconjugated
IsotypeIgG1, Kappa
Quantity100 µg
ReactivityHuman
HostMouse
Antibody TypePrimary
NCBI Full Gene Namekeratin 18
Concentration0.50 mg/mL
ImmunogenKeratin enriched fraction from human epidermoid carcinoma
ClonalityMonoclonal
TargetCytokeratin pan reactive

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patientsCell Reports MedicineJune 20, 2023Joann Diray-Arce, Slim Fourati, Naresh Doni Jayavelu, Ravi Patel, Cole Maguire, Ana C. Chang, Ravi Dandekar, Jingjing Qi, Brian H. Lee, Patrick van Zalm, et al.Anti-Human ACE-2 (535919) antibody,NOVUS,Cat#MAB9332-100 Anti-Human Cytokeratin (C-11) antibody,Biolegend,Cat#628602 Anti- CoV Spike protein (1A9) antibody,GeneTex,Cat#GTX632604 Anti-Human EPX (MM82.2.1) antibody,MAYO

(2) Expression and Therapeutic Targeting of TROP-2 in Treatment-Resistant Prostate CancerClinical Cancer ResearchJune 13, 2023Jamie M. Sperger, Kyle T. Helzer, Charlotte N. Stahlfeld, Dawei Jiang, Anupama Singh, Katherine R. Kaufmann, David J. Niles, Erika Heninger, Nicholas R. Rydzewski, Liguo Wang, et al.RRID:AB_389327), Anti-CD66B (BioLegend Cat# 305109, RRID:AB_2563170), Anti-Pan cytokeratin (BioLegend Cat# 628602, RRID:AB_439775 or Abcam Cat# ab49779, RRID:AB_869395), Anti-Androgen Receptor (Cell Signaling Technology

(3) Uridine-derived ribose fuels glucose-restricted pancreatic cancerNatureJune 1, 2023Nwosu ZC, Ward MH, Sajjakulnukit P, Poudel P, Ragulan C, Kasperek S, Radyk M, Sutton D, Menjivar RE, Andren A, et al.at 4 °C with a primary antibody for panCK (Mouse anti-cytokeratin, pan reactive; 1:100; BioLegend; 628602) diluted in CoDetection Antibody Diluent. Protease digestion was performed for 13 min at room temperature.

(4) Optimizing culturing conditions in patient derived 3D primary slice cultures of head and neck cancerFrontiers in OncologyMarch 30, 2023Maria do Carmo Greier, Annette Runge, Jozsef Dudas, Lukas Carpentari, Volker Hans Schartinger, Avneet Randhawa, Melissa Mayr, Monika Petersson, Herbert RiechelmanneBioscience™, ThermoFischer, Waltham, MA United States), cytokeratin (CK) (Alexa Fluor 488 conjugated) (#628601, BioLegend, San Diego, United States), and CD45 (Alex Fluor 594 conjugated (#304060, BioLegend, San

(5) Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive breast cancerFrontiers in oncologyJanuary 1, 2023Fang WB, Medrano M, Cote P, Portsche M, Rao V, Hong Y, Behbod F, Knapp JR, Bloomer C, Noel-Macdonnell J, et al.anti-VEGFR2 (Santa Cruz Biotechnology, cat no.sc-393163) and anti-Pan-Cytokeratin (Biolegend, cat no.628602). Cells were washed in PBS 3 times and incubated with the following secondary antibodies (1:1000): anti-rabbit-biotinylated

(6) PD-1 and ICOS coexpression identifies tumor-reactive CD4+ T cells in human solid tumorsJournal of Clinical InvestigationJune 15, 2022Rebekka Duhen et al.89601S); anti–MHC class II (BD Pharmingen, Tu39; no. 555556); and anti-cytokeratin (BioLegend, C-11; no. 628602). Antigen-antibody binding was visualized with TSA-Opal reagents (Akoya Biosciences). Detailed information

(7) Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunityCancer cellSeptember 13, 2021Hutton C, Heider F, Blanco-Gomez A, Banyard A, Kononov A, Zhang X, Karim S, Paulus-Hock V, Watt D, Steele N, et al.M5/114.15.2,Fluidigm,3209006B Anti-mouse cytokeratin-7 clone RCK105,Abcam,Ab9021 Anti-mouse pan-cytokeratin clone C-11,Biolegend,628602 Anti-mouse VIM 154Sm clone D21H3,Fluidigm,3154014A Anti-mouse RFP clone 8E5.G7,Rockland Inc,200-301-379 Anti-mouse

(8) Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinomaMolecular oncologySeptember 1, 2021Bade RM, Schehr JL, Emamekhoo H, Gibbs BK, Rodems TS, Mannino MC, Desotelle JA, Heninger E, Stahlfeld CN, Sperger JM, et al.554723). Following fixation and permeabilization, cells were stained for pan‐cytokeratin (C‐11, BioLegend, 628602, conjugated to A790 (Life Tech, A20189)). Putative CTC populations were defined by positive expression

(9) The Consequences of Soluble Epoxide Hydrolase Deletion on Tumorigenesis and Metastasis in a Mouse Model of Breast CancerInternational Journal of Molecular SciencesJuly 1, 2021Rushendhiran Kesavan, Timo Frömel, Sven Zukunft, Bernhard Brüne, Andreas Weigert, Ilka Wittig, Rüdiger Popp, Ingrid FlemingAcris antibodies, San Diego, CA, USA; #AM33039PU-N), anti-cytokeratin (1:400, Biolegend, San Diego, CA, USA; #628602), anti-Lyve1 (1:20, R&D Systems, Minneapolis, MN, USA; #AF 2125), anti-endomucin (1:50, eBioscience,

(10) Expansion of Circulating Tumor Cells from Patients with Locally Advanced Pancreatic Cancer Enable Patient Derived Xenografts and Functional Studies for Personalized MedicineCancersApril 20, 2020Rivera-Báez L, Lohse I, Lin E, Raghavan S, Owen S, Harouaka R, Herman K, Mehta G, Lawrence TS, Morgan MA, et al.Technology, Danvers, MA, USA), Mouse IgG1 anti-human anti-Pan-Keratin (1:500 Biolegend, San Diego, CA, USA, 628601), Mouse IgG2a anti-human anti-Cytokeratin 19 (1:500 Santa Cruz sc-6278), and Rat IgG2b anti-human CD45

(11) The Transcription Factor OVOL2 Represses ID2 and Drives Differentiation of Trophoblast Stem Cells and Placental Development in MiceCellsMarch 31, 2020Jeyarajah MJ, Jaju Bhattad G, Hillier DM, Renaud SJ.goat serum (ThermoFisher Scientific). Sections were immersed in a primary antibody specific for cytokeratin (628602, 1:400, BioLegend, San Diego, CA, USA), and then incubated with a mouse biotinylated secondary antibody,

(12) Antiviral Inflammation during Early Pregnancy Reduces Placental and Fetal Growth TrajectoriesJournal of immunology (Baltimore, Md. : 1950)February 1, 2020Baines KJ, Rampersaud AM, Hillier DM, Jeyarajah MJ, Grafham GK, Eastabrook G, Lacefield JC, Renaud SJ.(Thermo Fisher Scientific). Sections were immersed in primary Abs specific for cytokeratin (catalog no. 628602, 1:400; BioLegend) and vimentin (catalog no. MA5-11883, 1:50; Invitrogen) overnight at 4˚C. After washing,

(13) Quantitative analysis of taxane drug target engagement of microtubules in circulating tumor cells from metastatic castration resistant prostate cancer patients treated with CRXL301, a nanoparticle of docetaxelCancer drug resistance (Alhambra, Calif.)January 1, 2020Mukhtar E, Worroll D, Galletti G, Schuster S, Piha-Paul SA, Giannakakou P.antibody recognizing human cytokeratins 4, 5, 6, 8, 10, 13, and 18 (BioLegend, San Diego, CA catalog # 628602) conjugated to CF594 using Biotium Mix-n- Stain antibody labeling kit (catalog # 92236); (3) tubulin

(14) A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumorProceedings of the National Academy of Sciences of the United States of AmericaJune 4, 2019Florian S, Iwamoto Y, Coughlin M, Weissleder R, Mitchison TJ.

(15) Effect of co‑culture with amniotic epithelial cells on the biological characteristics of amniotic mesenchymal stem cellsMolecular medicine reportsJuly 1, 2018Ran LJ, Zeng Y, Wang SC, Zhang DS, Hong M, Li SY, Dong J, Shi MX.leukocyte antigen D‑related (HLA‑DR; cat. no. 307602; 1:100) and pan‑cytokeratins (Pan‑CK; cat. no. 628602; 1:250); which were all purchased from BioLegend, Inc. (San Diego, CA, USA). Cells were then incubated

(16) Impact of endoscopic stent insertion on detection of viable circulating tumor cells from obstructive colorectal cancerOncology lettersJanuary 1, 2018Yamashita S, Tanemura M, Sawada G, Moon J, Shimizu Y, Yamaguchi T, Kuwai T, Urata Y, Kuraoka K, Hatanaka N, et al.distinguish v‑CTCs as of epithelial origin, cells were stained with anti‑cytokeratin antibody (628502 and 628602; BioLegend, San Diego, CA, USA). To further distinguish v‑CTCs as of mesenchymal origin, cells were

(17) MicroRNA-200b regulates distal airway development by maintaining epithelial integrityScientific ReportsDecember 1, 2017Naghmeh Khoshgoo et al.immunofluorescence was performed using vimentin (Abcam; ab92547; 1:800) and cytokeratin (BioLegend, 628602, 1:200). Fetal lung explant culture For mice lung explant culture, lungs were isolated from E11.5

(18) Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patientsOncotargetMay 23, 2017Togo S, Katagiri N, Namba Y, Tulafu M, Nagahama K, Kadoya K, Takamochi K, Oh S, Suzuki K, Sakurai F, et al.1:20; Miltenyi Biotec), anti-vimentin (ab45939, 1:200; Abcam, Cambridge, UK), anti-pan-cytokeratin (628602, 1:100; BioLegend), anti-cytokeratin 19 (628502, 1:100; BioLegend), and anti-CEA (M707229, 1:50; Dako

(19) Multiparameter Single Cell Profiling of Airway Inflammatory CellsCytometry. Part B, Clinical cytometryJanuary 1, 2017Yao Y, Welp T, Liu Q, Niu N, Wang X, Britto CJ, Krishnaswamy S, Chupp GL, Montgomery RR.T4 156Gd,IL-6,DVS,3156011B,MQ2-13AS 159Tb,CD11c,DVS,3159001B,Bu15 160Gd,CD14,DVS,3160001B,M5E2 161Dy,Cytokeratin,BioLegend,628601,C-11 162Dy,CD80,DVS,3162010B,2D10.4 164Dy,CD15,DVS,3164001B,W6D3 165Ho,CD163,DVS,3165017B,GHI/61 168Er,IFN-γ,DVS,3168005B,B27 170Er,CD3,DVS,3170001B,UCHT1 171Yb,CD66b,BWH*,V10178,G10F5 173Yb,IL-8,BioLegend**,511402,E8N1 174Yb,CD62L,BWH*,V00751,DREG-56 176Yb,CD56,DVS,3176009B,N901 Antibodies

(20) ERG induces taxane resistance in castration-resistant prostate cancerNature CommunicationsDecember 1, 2014Giuseppe Galletti et al.sc-1694X); rabbit anti-FLAG (1:1,000 Sigma, F7425); pan-cytokeratin (1:1,000 BioLegend, clone C-11 cat # 628602 and Lot # B181240); αtubulin (1:1,000 Sigma, #T6199) and GAPDH (1:10,000 Abcam, sb-75834). Following

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Purified anti-Cytokeratin (pan reactive) from BioLegend

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Purified anti-Cytokeratin (pan reactive) from BioLegend

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